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QWhich genetic disorder is caused by excessive trinucleotide repeats (CAG)?

ID: #10199 Genetics 114 views
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#10199Q ID
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  • A Cystic fibrosis ✔ ✖
  • B PTC tasting ✔ ✖
  • C A quantitative analysis of genetic variation ✔ ✖
  • D An analysis of polygenic traits ✔ ✖
Correct Answer: Option D

Explanation

Huntington's disease is an autosomal dominant disorder that is caused by an abnormal expansion of CAG trinucleotide repeats in the huntingtin gene. The normal range of CAG repeats in this gene is 10 to 35, but in individuals with Huntington's disease, the number of CAG repeats is greater than 40, leading to the production of a toxic protein that damages nerve cells in the brain.

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