Q What is responsible for changing fibrinogen into fibrin during blood clotting?
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During the process of blood clotting, fibrinogen is converted into fibrin, a long, insoluble protein that forms a mesh-like network that helps to trap blood cells and form a clot. This process is initiated by the activation of prothrombin, a plasma protein, by the enzyme thrombin. Thrombin cleaves fibrinogen, releasing fibrinopeptides A and B, which allows fibrinogen to be polymerized into fibrin. The polymerization of fibrin is responsible for the formation of a stable blood clot.
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